7.3.2025

Doctoral thesis in Chemical Technolgy

M.Sc. (Eng.) Amirmohammad Ghafarihashjin’s doctoral thesis in Chemical Technology will be put forth for public defence at the Faculty of Science and Engineering at Åbo Akademi University.

The thesis is entitled Characterization Systems for Engineered Switchable Bioelectronics.

The public defence of the doctoral thesis takes place on 13 March 2025 at 1PM in auditorium Armfelt, Arken, Tehtaankatu 2, Turku. Professor Eleni Stavrinidou, Linköping University, Sweden, will serve as opponent and Docent Eleonora Macchia, Åbo Akademi University, as custos.

Summary

This work focused on the development and characterization of engineered switchable bioelectronics, with an emphasis on studying peptide conformational changes at electrode surfaces. Achieving on-demand control over peptide structures enables temporal signalling and offers insights into biological pathways, such as the Notch signalling system.

We introduced novel characterization techniques for switchable bioelectronics, developed new fabrication methods for OECTs, and addressed key operational stability challenges. These works have extended our understanding of bioelectronics, provided insights into peptide functionalization at electrode interfaces, and provided tools for studying them.

Amirmohammad Ghafarihashjin can be reached by email aghafari@abo.fi.

The doctoral thesis can be read online through the Doria publication archive.

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